Retin A Micro is a prescription-only water-based topical gel used to treat and prevent acne. It is applied nightly, or as directed by the prescribing doctor.
It is similar to Retin-A except that Retin A Micro uses an interesting delivery system. Retin A Micro can be applied immediately after washing the face, unlike Retin-A which required a 20-30 minute waiting period. This product is marketed by Ortho Neutrogena and comes in two strengths: 0.1% and 0.04% (referring to the concentration of the active ingredient, tretinoin).
Retin A Micro's active ingredient is tretinoin, an acne medication frequently prescribed by dermatologists. The delivery system is known as Microsponge® and is similar to the function of liposomes.
The Microsponge® delivery system consists of microspheres - microscopic particles made of a synthetic polymer. The tretinoin molecules are held within the microspheres. When Retin A Micro is applied to the skin, the microspheres prevent the surface of the skin from immediately absorbing the tretinoin - thus slowing and prolonging the delivery of the medication. As an added side-effect of this delivery system, Retin A Micro doesn't irritate the skin or cause it to look "shiny" like Retin A does. Microspheres do not actually penetrate the skin and enter cells, the way natural liposomes do.
Although the exact method of Retin A Micro's function is unknown, researchers theorize that the active ingredient breaks up existing clumps of skin cells and prevents new clumps from forming. This action causes existing acne blemishes to be reduced and helps prevent new blemishes from forming.
More information on what causes acne.
Our staff of experts have rated a number of products in this category and have listed their recommendations.
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Retin A Micro should not be used by women who are breastfeeding, pregnant, or thinking of becoming pregnant. In a recent clinical trial, 50% of the test subjects developed skin irritation, peeling, itching, burning or stinging. Other subjects had severe irritation, blistering, and crusting. Due to these side effects and the high cost of this prescription medication, we must rate Retin A Micro a Do Not Buy.